Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents01:24

Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents

In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
Drugs for Treatment of Ulcerative Colitis in IBD01:29

Drugs for Treatment of Ulcerative Colitis in IBD

Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide generation. 
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Hypersensitivity Reactions: Cytolytic Reactions01:01

Hypersensitivity Reactions: Cytolytic Reactions

Type II hypersensitivity involves IgG and IgM antibodies targeting cell surface antigens, leading to cell destruction. This can occur through complement activation, antibody-dependent cell-mediated cytotoxicity (ADCC), or acting as opsonins for phagocytosis. When excessive, these reactions cause significant tissue damage.Drug-induced hemolytic anemia is a common example, where drugs like penicillin or cephalosporins bind to red blood cells, forming drug-protein complexes. These complexes...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing RNA extraction methods to face the variations in RNA quality using two human biological matrices.

Molecular biology reports·2023
Same author

Misdiagnosis in Epidermolysis Bullosa: Yet Another Burden on Patients and their Families.

Actas dermo-sifiliograficas·2023
Same author

Multifocal rapidly involuting congenital haemangiomas.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same author

Misdiagnosis in Epidermolysis Bullosa: Yet Another Burden on Patients and their Families.

Actas dermo-sifiliograficas·2022
Same author

Toxic Epidermal Necrolysis in a Boy: Successful Treatment With Cyclosporine A.

Actas dermo-sifiliograficas·2020
Same author

Slit1 Protein Regulates SVZ-Derived Precursor Mobilization in the Adult Demyelinated CNS.

Frontiers in cellular neuroscience·2020

Related Experiment Video

Updated: Jul 22, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Bullous eruption induced by tranexamic acid

C Carrión-Carrión, J del Pozo-Losada, R Gutierrez-Ramos

    The Annals of Pharmacotherapy
    |November 1, 1994
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
    04:12

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

    Published on: January 19, 2024

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
    07:22

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

    Published on: March 14, 2025

    Related Experiment Videos

    Last Updated: Jul 22, 2026

    Granulocyte-dependent Autoantibody-induced Skin Blistering
    12:23

    Granulocyte-dependent Autoantibody-induced Skin Blistering

    Published on: October 12, 2012

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
    04:12

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

    Published on: January 19, 2024

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
    07:22

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

    Published on: March 14, 2025