Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Programmed cell death. A rich harvest

M O Hengartner1

  • 1Cold Spring Harbor Laboratory, New York 11724.

Current Biology : CB
|October 1, 1994
PubMed
Summary
This summary is machine-generated.

Researchers identified genes influencing programmed cell death in Drosophila. This discovery advances our understanding of cell death mechanisms and positions Drosophila at the forefront of this critical research area.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Cell death and differentiation·2014
Same author

Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans.

Cell death and differentiation·2014
Same author

Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans.

Cell death and differentiation·2012
Same author

PaxDb, a database of protein abundance averages across all three domains of life.

Molecular & cellular proteomics : MCP·2012
Same author

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012.

Cell death and differentiation·2011
Same author

A lectin-mediated resistance of higher fungi against predators and parasites.

Molecular ecology·2011
Same journal

A global response contributes to tissue size robustness upon local induction of apoptosis.

Current biology : CB·2026
Same journal

Prebilaterian origin of monoaminergic signaling.

Current biology : CB·2026
Same journal

CLASP-dependent microtubule stabilization generates microtubule-based protrusive forces during Drosophila epithelial morphogenesis.

Current biology : CB·2026
Same journal

Pigeons make slow, divergent eye movements during flight and large, convergent eye movements when landing.

Current biology : CB·2026
Same journal

Temperature signals drive grass secondary cell wall thickening.

Current biology : CB·2026
Same journal

Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress.

Current biology : CB·2026
See all related articles

Area of Science:

  • Developmental Biology
  • Genetics
  • Cell Biology

Background:

  • Programmed cell death, or apoptosis, is crucial for development and tissue homeostasis.
  • Understanding the genetic regulation of apoptosis is fundamental to many biological processes.

Purpose of the Study:

  • To identify and characterize genes that regulate programmed cell death in the model organism Drosophila.
  • To establish Drosophila melanogaster as a key model for dissecting conserved cell death pathways.

Main Methods:

  • Utilizing genetic screens in Drosophila to identify mutations affecting cell death phenotypes.
  • Employing molecular and cellular techniques to analyze gene function and pathway interactions.

Main Results:

Related Experiment Videos

  • Several novel genes involved in the regulation of programmed cell death were identified.
  • The study elucidated conserved genetic pathways controlling apoptosis in Drosophila.

    • Conclusions:

    • The identification of these genes significantly advances the field of cell death research.
    • Drosophila melanogaster serves as a powerful model for studying the genetic basis of programmed cell death.