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Eosinophilic gastroenteritis presenting with colitis and cholangitis

D Schoonbroodt1, Y Horsmans, A Laka

  • 1Department of Gastroenterology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium.

Digestive Diseases and Sciences
|February 1, 1995
PubMed
Summary

Eosinophilic gastroenteritis, a rare gastrointestinal disorder, can present with colitis and cholangitis. This case highlights the first documented instance of associated cholangitis, suggesting a potential link with hypereosinophilic syndrome.

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Area of Science:

  • Gastroenterology
  • Hepatology
  • Pathology

Background:

  • Eosinophilic gastroenteritis (EG) is a rare inflammatory condition primarily affecting the stomach and intestines.
  • While large bowel involvement is known, concurrent biliary tract disease is infrequently reported.

Observation:

  • This report details a unique case of EG manifesting with both colitis and cholangitis.
  • The association of cholangitis was confirmed through both radiological and histological examinations.

Findings:

  • This represents the first documented case of eosinophilic gastroenteritis with radiologically and histologically confirmed cholangitis.
  • The simultaneous presentation in the biliary and gastrointestinal tracts suggests a potential shared pathophysiology, possibly related to hypereosinophilic syndrome (HES).

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Implications:

  • This case broadens the understanding of EG's potential systemic manifestations beyond the gastrointestinal tract.
  • It underscores the importance of considering EG in patients with unexplained colitis and cholangitis, especially when evaluating for hypereosinophilic conditions.