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Tumor blood flow measured using dynamic computed tomography

H Hattori¹, T Miyoshi, J Okada

¹Department of Radiology, Kanto Central Hospital, Tokyo, Japan.

Investigative Radiology

|October 1, 1994

Summary

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A new dynamic computed tomography (DCT) method accurately measures tumor blood flow (TBF). This reliable technique was validated against thermal clearance and positron-emission tomography (PET) in patients with superficial tumors.

Area of Science:

Medical Imaging
Oncology
Radiology

Background:

Accurate measurement of tumor blood flow (TBF) is crucial for cancer diagnosis and treatment monitoring.
Dynamic computed tomography (DCT) offers a potential non-invasive method for assessing TBF.

Purpose of the Study:

To develop and validate a novel DCT method for measuring TBF in superficial tumors.
To compare the TBF measurements obtained by DCT with established methods.

Main Methods:

The study involved 27 patients with superficial tumors.
Tumor blood flow was measured using the new DCT method.
Comparisons were made with thermal clearance (relative TBF) and oxygen-15-gas positron-emission tomography (PET) for TBF.

Main Results:

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A linear relationship was observed between the TBF values measured by DCT and the comparative methods.
The DCT method demonstrated a strong correlation with established TBF measurement techniques.

Conclusions:

The newly developed DCT method provides reliable and accurate data for measuring tumor blood flow.
This DCT technique shows promise as a valuable tool in oncological imaging and research.