Terfenadine toxicosis in dogs

Terfenadine is an antihistamine that has been reported to be safe for use in human beings and animals. This report focuses on an index case of terfenadine toxicosis and several cases of terfenadine toxicosis reported to the National Animal Poison Control Center from 1987 through 1992. Adverse effects of terfenadine can be seen with dosages as low as 6.6 mg/kg of body weight. Any accidental exposure to terfenadine should be treated by inducing emesis and by administering activated charcoal, along with supportive care.