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Cadmium and hypertension
S K Bakshi1, K P Chawla, R N Khandekar
1Department of General Medicine, Seth GS Medical College, Parel, Bombay.
Insights
This study investigated whole blood cadmium levels in hypertensive patients compared to normotensive individuals. Results show a statistically significant difference, suggesting a link between cadmium and hypertension.
Area of Science:
- Environmental Health
- Cardiovascular Disease Research
- Trace Element Analysis
Background:
- Essential hypertension is a prevalent condition in modern society.
- The role of cadmium, a toxic trace element, in hypertension development is debated.
- Previous research on cadmium and hypertension has yielded conflicting results.
Purpose of the Study:
- To quantify and compare whole blood cadmium levels in hypertensive and normotensive subjects.
- To determine if cadmium levels are significantly different between these two groups.
Main Methods:
- Blood samples were collected from thirty hypertensive patients.
- Blood samples were collected from thirty normotensive control subjects.
- Whole blood cadmium concentrations were measured and statistically analyzed.
Main Results:
- A statistically significant difference in whole blood cadmium levels was observed between the groups (p < 0.05).
- Hypertensive individuals exhibited different cadmium levels compared to normotensive individuals.
Conclusions:
- The findings suggest a significant association between elevated whole blood cadmium levels and essential hypertension.
- Further research is warranted to elucidate the precise role of cadmium in the pathogenesis of hypertension.
Abstract:
Hypertension is a very common and important disease of modern civilised life. There are comflicting reports about cadmium, a trace element in the genesis of essential hypertension. The present study was conducted to estimate the cadmium levels in whole blood in the normal group of thirty subjects who were normotensive and the same was compared to that of thirty hypertensive patients and the levels were found to be statistically significant (p < 0.05).