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Aromatase activity in an estrogen-producing adrenocortical carcinoma in a young man
M Kimura1, N Itoh, T Tsukamoto
1Department of Urology, Sapporo Medical University School of Medicine, Japan.
The Journal of Urology
|March 1, 1995
Abstract:
We report on a 19-year-old man with adrenocortical adenoma producing an excessive amount of estrogen. Determination of aromatase activity of the carcinoma tissue revealed its marked enhancement compared with that of 3 normal adrenal glands and the adipose tissue. The enhanced activity of aromatase was mainly responsible for the overproduction of estrogen in the adrenocortical carcinoma of our case.