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Narcotic antagonists. Treatment tool for addiction
The Nursing Clinics of North America
|September 1, 1976
Summary
Narcotic antagonists, like naltrexone, show promise for treating opiate addiction by blocking opiate effects. Research is ongoing to evaluate their biochemical effects and clinical use.
Area of Science:
- Pharmacology
- Addiction Medicine
- Neuroscience
Background:
- Narcotic antagonists are under investigation for their potential in treating opiate addiction.
- These drugs function by blocking the euphoric effects of opiates.
Observation:
- Naltrexone emerges as a leading candidate due to its effective blockade, long duration, and minimal side effects.
- Current research aligns with Wikler's biobehavioral theory of conditioned abstinence.
Findings:
- Narcotic antagonists offer a novel treatment approach for opiate addiction.
- Naltrexone demonstrates significant potential for clinical application.
Implications:
- These findings suggest a future where narcotic antagonists play a key role in addiction treatment.
- Further research across seven US centers may lead to wider clinical availability.