Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[The desmosome: structure, function and acquired pathology]

E Cozzani1, J F Nicolas, A Reano

  • 1INSERM U.346, Clinique Dermatologique, Université Claude-Bernard, Hôpital Ed.-Herriot, Lyon, France.

Pathologie-Biologie
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A geriatric re-evaluation clinic is associated with fewer unplanned returns in the Emergency Department: an observational case-control study.

European geriatric medicine·2022
Same author

Relevance of frailty and functional limitations in elderly patients treated with noninvasive ventilation in the ED.

The American journal of emergency medicine·2020
Same author

The adsorption kinetics of metal ions onto different microalgae and siliceous earth.

Water research·2001
Same author

Plasma vascular endothelial growth factor levels in scleroderma are not correlated with disease activity.

Acta dermato-venereologica·2001
Same author

Modulation of endothelin-1 in normal human keratinocytes by UVA1/B radiations, prostaglandin E2 and peptidase inhibitors.

Experimental dermatology·2000
Same author

Penetration of human metastatic melanoma cells through an authentic dermal-epidermal junction is associated with dissolution of native collagen types IV and VII.

Melanoma research·2000
Same journal

Pathologie-biologie·2020
Same journal

Antibacterial and antibiofilm activities of Laurus nobilis L. essential oil against Staphylococcus aureus strains associated with oral infections.

Pathologie-biologie·2015
Same journal

[Not Available].

Pathologie-biologie·2015
Same journal

Oxidative damage and histopathological changes in lung of rat chronically exposed to nicotine alone or associated to ethanol.

Pathologie-biologie·2015
Same journal

Biological diagnosis of diabetes mellitus.

Pathologie-biologie·2015
Same journal

Association of CagPAI integrity with severeness of Helicobacter pylori infection in patients with gastritis.

Pathologie-biologie·2015
See all related articles

Skin

Area of Science:

  • Dermatology and cell biology
  • Investigates the structural integrity of the epidermis
  • Focuses on cell-to-cell adhesion mechanisms

Context:

  • The epidermis provides skin's resistance to external forces.
  • Desmosomes are crucial for keratinocyte adhesion and epidermal strength.
  • Fifteen desmosomal proteins are currently known to be involved.

Purpose:

  • To elucidate the role of desmosomes in maintaining epidermal integrity.
  • To understand the molecular interactions underlying cell adhesion in the skin.
  • To highlight the significance of desmosomal proteins in skin structure.

Summary:

  • Desmosomes, through interactions between desmosomal proteins and cytoskeletal filaments, ensure epidermal cell adhesion and skin resistance.

Related Experiment Videos

  • The study highlights fifteen characterized desmosomal proteins essential for this adhesion.
  • Autoimmune conditions like pemphigus demonstrate the critical role of desmosomes in epidermal integrity.

    • Impact:

    • Provides foundational knowledge for understanding skin barrier function.
    • Informs research into autoimmune blistering diseases like pemphigus.
    • Contributes to the understanding of keratinocyte adhesion and epidermal structure.