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Updated: Aug 9, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Venous diameter and compliance after deep venous thrombosis
M H Meissner1, R A Manzo, R O Bergelin
1Department of Surgery, University of Washington School of Medicine, Seattle.
Deep vein thrombosis (DVT) can reduce venous diameter, but complete recanalization restores normal size. Chronic venous compliance is unaffected by DVT, even with residual disease.
Area of Science:
- Vascular Ultrasound
- Venous Physiology
- Thrombosis Research
Background:
- Deep vein thrombosis (DVT) can lead to chronic venous changes.
- Assessing venous diameter and compliance post-DVT is crucial for understanding long-term outcomes.
Purpose of the Study:
- To evaluate venous diameter changes and compliance after deep vein thrombosis (DVT).
- To compare venous dimensions and response to Valsalva's maneuver in DVT patients versus normal subjects.
Main Methods:
- Duplex sonography was employed to measure common femoral, superficial femoral, and popliteal vein diameters.
- Measurements were taken in 56 patients post-DVT and 17 healthy controls.
- Venous compliance was assessed via diameter changes during Valsalva's maneuver.
Main Results:
- Segments with residual DVT disease showed significantly smaller diameters compared to the contralateral healthy side.
- Completely recanalized segments exhibited diameters and diameter indices similar to normal subjects.
- Venous distensibility with Valsalva's maneuver was not significantly different from normal in DVT patients, regardless of disease resolution.
Conclusions:
- Venous diameter decreases after DVT but normalizes with complete recanalization.
- Chronic venous compliance is not significantly altered by DVT, even in the presence of residual disease.
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