Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immunosuppression by seminal plasma.

Immunology today·2014
Same author

The role of neuroendocrine cells in prostate cancer: a comprehensive review of current literature and subsequent rationale to broaden and integrate current treatment modalities.

Current medicinal chemistry·2013
Same author

Retinoids, vitamin D, invasion, and metastasis.

Current oncology (Toronto, Ont.)·2012
Same author

The role of transglutaminases in the pathophysiology of prostate cancer.

Current oncology (Toronto, Ont.)·2011
Same author

Induction of Cancer of the Cervix Uteri in Relation to the Oestrus Cycle.

British journal of cancer·2011
Same author

Screening for prostate cancer: Controversy? What controversy?

Current oncology (Toronto, Ont.)·2009

Related Experiment Video

Updated: Jul 9, 2026

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
10:23

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

Published on: December 1, 2017

Sperm-induced urolithiasis in the rat

R Stein-Werblowsky1, R J Ablin

  • 1Shaare Zedek Hospital, Jerusalem, Israel.

European Journal of Epidemiology
|October 1, 1994
PubMed
Summary
This summary is machine-generated.

Experimental insemination in rats caused sperm to precipitate and form bladder stones. This suggests that sperm in the bladder may contribute to bladder lithiasis, explaining its higher prevalence in men.

More Related Videos

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Related Experiment Videos

Last Updated: Jul 9, 2026

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
10:23

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

Published on: December 1, 2017

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Area of Science:

  • Urology
  • Reproductive Biology
  • Biochemistry

Background:

  • Bladder lithiasis (bladder stones) is more common in men than women.
  • The exact causes of bladder stone formation are not fully understood.
  • The role of seminal fluid components in stone formation requires further investigation.

Purpose of the Study:

  • To investigate the potential role of sperm in the formation of intravesical precipitation and bladder stones.
  • To explore the link between experimental insemination and the development of bladder lithiasis.
  • To determine if intravesical sperm could explain the gender disparity in bladder stone prevalence.

Main Methods:

  • Experimental insemination of autologous or homologous sperm into the ventral prostate or bladder neck of male rats.
  • Observation and analysis of intravesical precipitation and stone formation.
  • Histopathological examination of induced stones.

Main Results:

  • Experimental insemination led to the induction of intravesical precipitation and stone formation in male rats.
  • The induced stones were composed of precipitated seminal components.
  • The findings provide a potential mechanism for sperm-induced bladder lithiasis.

Conclusions:

  • Intravesical sperm, resulting from experimental insemination, can induce bladder stone formation.
  • Clinical conditions leading to intravesical sperm may contribute to bladder lithiasis in humans.
  • This mechanism may be relevant to the higher prevalence of bladder stones in men.