Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Knot tying at flexible endoscopy

C P Swain1, S S Kadirkamanathan, F Gong

  • 1Gastrointestinal Science Research Unit, Royal London Hospital, Whitechapel, United Kingdom.

Gastrointestinal Endoscopy
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intramural twin pregnancy after in-vitro fertilization.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
Same author

A study on serum pro-neurotensin (PNT), furin, and zinc alpha-2-glycoprotein (ZAG) levels in patients with acromegaly.

Journal of endocrinological investigation·2022
Same author

Bone microarchitecture impairment in prolactinoma patients assessed by HR-pQCT.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2022
Same author

Pregnancy outcome after in-vitro fertilization/intracytoplasmic sperm injection in women with congenital uterus didelphys.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2021
Same author

Canine-specific tail-in, head-out sperm agglutination.

Reproduction in domestic animals = Zuchthygiene·2021
Same author

Serum glypican4 and glycosylphosphatidylinositol-specific phospholipase D levels are associated with adipose tissue insulin resistance in obese subjects with different glucose metabolism status.

Journal of endocrinological investigation·2020
Same journal

Adverse events associated with endoscopic retrograde cholangiopancreatography (ERCP) and ERCP-related procedures.

Gastrointestinal endoscopy·2026
Same journal

Quality measures in the design, conduct, and reporting of endoscopic research.

Gastrointestinal endoscopy·2026
Same journal

Location of GI lesions with bleeding potential in patients with iron deficiency anemia: a multicenter prospective study.

Gastrointestinal endoscopy·2026
Same journal

TEMPORARY REMOVAL: Sustainability indicators for gastrointestinal endoscopy: a framework proposed by the Canadian Association of Gastroenterology and the American Society for Gastrointestinal Endoscopy.

Gastrointestinal endoscopy·2026
Same journal

Clinical Outcomes of Primary versus Conversion Endoscopic Ultrasound-Guided Gallbladder Drainage after Percutaneous Drainage: A Multicenter Study.

Gastrointestinal endoscopy·2026
Same journal

Remimazolam versus Midazolam for Moderate Sedation in Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Gastrointestinal endoscopy·2026
See all related articles

New endoscopic knotting techniques enable secure closures during flexible endoscopy. These methods overcome access challenges and have proven effective in human and animal studies for various medical applications.

Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Medical Device Development

Background:

  • Knot tying during flexible endoscopy presents challenges due to limited access and instrument manipulation.
  • Existing endoscopic suturing methods require improved knot security and ease of application.
  • The development of novel knotting techniques is crucial for advancing minimally invasive endoscopic procedures.

Purpose of the Study:

  • To develop and evaluate four novel knotting techniques for flexible endoscopic applications.
  • To assess the feasibility and security of endoscopically tied knots compared to traditional surgical knots.
  • To demonstrate the clinical utility of these techniques in various endoscopic interventions.

Main Methods:

  • Four new knotting techniques were developed: half hitches with knot-pusher, thread-locking device, self-tightening slip-knot, and externally releasable knot.

Related Experiment Videos

  • Techniques were tested on postmortem human stomachs and in survival studies in dogs.
  • Clinical applications included anti-reflux operations, securing nasogastric tubes, and anchoring pH radio-telemetry capsules.

    • Main Results:

    • All four developed knotting techniques were found to be feasible for use during flexible endoscopy.
    • Endoscopically tied knots demonstrated comparable security to surgically hand-tied knots.
    • Successful clinical applications in humans included esophageal reflux treatment and long-term nasogastric tube fixation.

    Conclusions:

    • Knot tying is achievable and reliable using various new techniques during flexible endoscopy.
    • These novel endoscopic knotting methods offer a secure and effective alternative to traditional surgical suturing.
    • The successful implementation in human patients highlights the potential of these techniques for diverse endoscopic procedures.