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Urolithiasis and phytotherapy

F Grases1, G Melero, A Costa-Bauzá

  • 1Department of Chemistry, University of Balearic Islands, Palma de Mallorca, Spain.

International Urology and Nephrology
|January 1, 1994
PubMed
Summary

Seven plant infusions showed potential benefits for kidney stone prevention in rats, possibly due to disinfectant and solvent actions. However, more effective and safe alternatives are available for treating urolithiasis.

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Area of Science:

  • Phytotherapy
  • Urology
  • Pharmacology

Background:

  • Kidney stone (urolithiasis) formation is a significant health concern.
  • Herbal remedies are traditionally used for various ailments, including kidney stones.
  • Understanding the efficacy of medicinal plants is crucial for evidence-based practice.

Purpose of the Study:

  • To investigate the effects of seven specific plant infusions on key risk factors of kidney stone formation.
  • To evaluate the potential of these herbs in preventing and treating urolithiasis.

Main Methods:

  • Female Wistar rats were used as the experimental model.
  • The study assessed variations in urinary citrate, calcium, phosphate, pH, and diuresis.
  • Infusions of Verbena officinalis, Lithospermum officinale, Taraxacum officinale, Equisetum arvense, Arctostaphylos uva-ursi, Arctium lappa, and Silene saxifraga were administered.

Main Results:

  • The plant infusions influenced urolithiasis risk factors.
  • Beneficial effects were observed, potentially linked to disinfectant properties and saponins.
  • A solvent action on uric stones was suggested, attributed to the basifying capacity of some infusions.

Conclusions:

  • The studied herb infusions demonstrate some positive effects on urolithiasis in rats.
  • These effects may involve disinfectant and urine-alkalizing mechanisms.
  • While showing promise, more effective and equally safe therapeutic options are currently known.

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