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Epistaxis, von Willebrand's type bleeding diathesis and Wilms' tumour: a case report

P V Lim1, J D Mason, D Walker

  • 1Department of Otorhinolaryngology, University Hospital, Nottingham.

Insights

Persistent nosebleeds in an infant were linked to Wilms' tumour and a bleeding disorder. Treating the tumour with chemotherapy successfully managed the bleeding diathesis and epistaxis.

Area of Science:

  • Pediatric Oncology
  • Hematology

Background:

  • Wilms' tumour is a rare kidney cancer primarily affecting young children.
  • Von Willebrand's disease is a common inherited bleeding disorder.

Observation:

  • A seven-month-old infant presented with persistent epistaxis (nosebleeds).
  • The infant was diagnosed with Wilms' tumour and an associated von Willebrand's type bleeding diathesis.

Findings:

  • Successful management of epistaxis required addressing the underlying Wilms' tumour.
  • Chemotherapy treatment for the Wilms' tumour led to the correction of the bleeding diathesis.

Implications:

  • This case highlights the importance of investigating bleeding disorders in children with Wilms' tumour.
  • Effective cancer treatment can resolve associated hematological abnormalities, improving patient outcomes.

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