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Updated: Aug 11, 2026

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
Published on: May 19, 2018
Primary care approach to lymphadenopathy
1Division of Hematology/Oncology, University of Massachusetts Medical Center, Worcester.
Abstract:
Lymphadenopathy is a common presenting symptom. It is a manifestation of many disease processes ranging from self-limiting ones to those that are incurable and fatal. The diagnostic factors used to evaluate the etiology of one or more enlarged lymph nodes include: the age of the patient, the clinical history, the physical examination, and the anatomic location/nodal history and characteristics. With the selection of the proper tests, unnecessary or invasive treatments can be avoided. Ultimately, when a neoplastic process is suspected, a lymph node biopsy is the definitive test.
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