Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extraversion as a modifying factor in catecholamine and behavioral responses to ethanol

P Netter1, W Vogel, T Rammsayer

  • 1Department of Psychology, University of Giessen, Germany.

Psychopharmacology
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COVID-19 epidemic phases: Criteria, challenges and issues for the future.

Bulletin de l'Academie nationale de medecine·2020
Same author

[Covid-19 epidemic phases: Criteria, challenges and issues for the future].

Bulletin de l'Academie nationale de medecine·2020
Same author

Review article: moving towards common therapeutic goals in Crohn's disease and rheumatoid arthritis.

Alimentary pharmacology & therapeutics·2017
Same author

Fibroblast Growth Factor 23 drives MMP13 expression in human osteoarthritic chondrocytes in a Klotho-independent manner.

Osteoarthritis and cartilage·2016
Same author

Oxidative stress-induced expression of HSP70 contributes to the inhibitory effect of 15d-PGJ2 on inducible prostaglandin pathway in chondrocytes.

Free radical biology & medicine·2014
Same author

8th International Meeting of "Lorraine Pole of Cartilage Engineering". Foreword.

Bio-medical materials and engineering·2014
Same journal

GlyT1 inhibition enhances working memory in the mouse TUNL task and normalizes NMDA antagonist-induced network activity.

Psychopharmacology·2026
Same journal

Effects of repeated treatment with opioids that vary in mu opioid receptor efficacy on pain-depressed locomotor behavior in mice.

Psychopharmacology·2026
Same journal

Cannabidiol in the anterior insular cortex attenuates chronic neuropathic pain and comorbid anxiety- and depression-like behaviors: involvement of CB<sub>1</sub> and 5-HT<sub>1A</sub> receptor signaling.

Psychopharmacology·2026
Same journal

Fentanyl decreases arterial blood oxygen saturation more than furanylfentanyl in mice due to increased apnea.

Psychopharmacology·2026
Same journal

Suicide attempt risk among patients receiving methylphenidate: a retrospective cohort study.

Psychopharmacology·2026
Same journal

Investigating the impact of serotonergic psychedelic drugs, MDMA and ketamine on social cognition in psychiatric disorders: A scoping review.

Psychopharmacology·2026
See all related articles

Introverts showed higher norepinephrine increases and greater anxiety reduction under stress and ethanol, contrary to Eysenck's drug postulate. Their performance declined despite elevated catecholamines, suggesting central nervous system differences.

Area of Science:

  • Psychology
  • Neuroscience
  • Pharmacology

Background:

  • Eysenck's drug postulate suggests introverts are less susceptible to sedatives like ethanol.
  • Individual differences in stress and ethanol response are linked to catecholamine levels.

Purpose of the Study:

  • To investigate catecholamine responses to stress and ethanol in introverts and extraverts.
  • To test Eysenck's drug postulate regarding introverts' susceptibility to ethanol.

Main Methods:

  • Forty-four males received ethanol or placebo, followed by a stressful mental arithmetic task.
  • Plasma catecholamines (norepinephrine) and psychological self-ratings were measured.
  • Performance on the arithmetic task was assessed for quality and quantity.

Related Experiment Videos

Main Results:

  • No initial difference in catecholamine response between introverts and extraverts.
  • Both ethanol and placebo increased norepinephrine (NE) more in introverts (Ex -) than extraverts (Ex +).
  • Introverts exhibited greater anxiety reduction, relaxation, and performance decrements despite higher NE.

Conclusions:

  • Eysenck's drug postulate requires modification; introverts may have higher central nervous system NE depletion under certain stressors.
  • Observed higher plasma NE in introverts correlated with decreased performance and activation.
  • Arousal theory predictions were not fully supported by these findings.