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[Continuous partial epilepsy disclosing diabetes mellitus]

J P Cochin1, D Hannequin, T Delangre

  • 1Clinique Neurologique, CHU Charles-Nicolle, Rouen.

Revue Neurologique
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

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Continuous partial epilepsy (CPE) can be caused by high blood sugar without ketosis. Prompt insulin therapy and rehydration effectively resolved seizures in a patient with CPE and hyperglycemia.

Area of Science:

  • Neurology
  • Endocrinology
  • Metabolic Disorders

Background:

  • Continuous partial epilepsy (CPE) presents as focal motor seizures with concordant EEG findings.
  • CPE is associated with cortical lesions and metabolic disorders, including decompensated diabetes mellitus.

Observation:

  • A 54-year-old female presented with CPE, exhibiting normal CT and MRI findings.
  • Biochemical analysis revealed significant hyperglycemia without ketosis, acidosis, or hyperosmolality.

Findings:

  • Insulin therapy rapidly normalized blood glucose levels, leading to the complete resolution of seizures.
  • Epileptic seizures are common in hyperglycemia without ketosis (25% of cases), often presenting as partial motor seizures.

Implications:

Related Experiment Videos

  • CPE induced by hyperglycemia without ketosis is treatable with insulin therapy, offering a rapid cure.
  • Measuring blood glucose is crucial for diagnosing hyperglycemia without ketosis in CPE patients, enabling timely insulin and rehydration treatment.