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[Epileptic seizures and treatment with ifosfamide-mesna]
H Somma-Mauvais1, P Farisse, J R Viallat
1Service d'Explorations Fonctionnelles du Système Nerveux, CHU, Hôpital Sainte-Marguerite, Marseille.
Revue Neurologique
|January 1, 1994
Abstract:
Generalized and partial seizures with secondary generalization were observed during ifosfamide-mesna (IFO) treatment in a patient with lung epidermoid carcinoma. Seizures appeared in a stereotyped manner on the 3rd of the 4th and 6th day of treatment with IFO. Partially resolutive confusion was observed after the last cure. Brain CTS were normal. The responsibility of IFO is considered in the development of these neurological toxic manifestations.