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[Lung transplantation in pulmonary hypertension]
1Klinik für Herz- u. Gefässchirurgie, Christian-Albrechts-Universität zu Kiel.
Zeitschrift Fur Kardiologie
|January 1, 1994
Summary
Lung transplantation is the primary surgical option for severe pulmonary hypertension. While heart-lung transplants offer the best outcomes, single and double lung transplants are increasingly used despite higher complication risks.
Area of Science:
- Cardiology
- Thoracic Surgery
- Pulmonology
Context:
- Pulmonary hypertension (PH) has limited medical treatment options.
- Surgical interventions are primarily for pulmonary embolism, with lung transplantation being the main option for primary PH and Eisenmenger Syndrome.
Purpose:
- To review the surgical treatment options for pulmonary hypertension, including heart-lung, single lung, and double lung transplantation.
- To discuss the indications, outcomes, and complications associated with different lung transplantation techniques for PH.
Summary:
- Lung transplantation, including heart-lung (HLTx), single lung (SLTx), and double lung (DLTx) transplantation, is the main surgical approach for severe pulmonary hypertension.
- Indications are individualized based on PH severity, right ventricular failure, and correctability of underlying conditions.
- While HLTx offers optimal results, SLTx and DLTx are increasingly performed due to organ scarcity, though SLTx presents significant early and late complications.
Impact:
- Lung transplantation offers a survival rate of 70% at 1 year and 60% at 5 years for pulmonary hypertension patients.
- The optimal type of lung transplantation for pulmonary hypertension remains an area of ongoing research and definition.