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Monoclonal antibody S37 induces apoptosis in bovine T lymphoma cells
T Shinagawa1, N Ishiguro, M Horiuchi
1Department of Veterinary Public Health, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
The Journal of Veterinary Medical Science
|October 1, 1994
Abstract:
Influences of 38 monoclonal antibodies (mAbs) on the growth of bovine T lymphoma cells (BTL-27) were examined. One of them, S37, inhibited the cell growth strikingly when it was added to the cultures. S37-treated cells showed DNA fragmentation containing approximately 200-base pair multiple patterns and chromatin condensation. This evidence suggested that mAb S37 induced apoptosis in BTL-27 cells.