[Cause of rare pulmonary tumors. Two cases of pulmonary carcinosarcoma]

Two cases of primary pulmonary carcinosarcoma in men, aged 59 and 57 years, have been described. These are 100-th and 101-st descriptions in the world literature, being the second and third in Poland. The preoperative diagnosis of malignant neoplasm of endobronchial tumour was established on the basis of cytologic examination of sputum and specimen from bronchus. While the peripheral tumour was diagnose on the basis of fine needle transthoracic biopsy. The ultimate diagnosis was made by relying on histological examination, as well as after application of monoclonal antibodies. Cytokeratin and vimentin expression were detected in endobronchial neoplasm, but only cytokeratin expression was disclosed in the neoplasm peripherally in the lung parenchyma. The authors focus the attention on the increase, evidenced in the last ten years, of primary malignant and non-malignant, uniform and mixed mesenchymal tumours of the lungs, as well as on the relevant new problems and difficulties in microscopic preoperative diagnosis.