Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Respiratory dysfunction in Parkinson's disease

¹Department of Internal Medicine, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.

Clinics in Chest Medicine

|December 1, 1994

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of interventions for tuberculosis prevention and care in South Africa - a systematic review of mathematical modelling studies.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2023

Same author

Impact of root hairs on microscale soil physical properties in the field.

Plant and soil·2022

Same author

Significance of root hairs for plant performance under contrasting field conditions and water deficit.

Annals of botany·2020

Same author

Significance of root hairs at the field scale - modelling root water and phosphorus uptake under different field conditions.

Plant and soil·2020

Same author

Surface tension, rheology and hydrophobicity of rhizodeposits and seed mucilage influence soil water retention and hysteresis.

Plant and soil·2019

Same author

Plant exudates may stabilize or weaken soil depending on species, origin and time.

European journal of soil science·2017

Same journal

Pneumonia Reimagined: Host, Microbe, and the Shifting Landscape of Disease.

Clinics in chest medicine·2026

Same journal

Advocacy in Pneumonia.

Clinics in chest medicine·2026

Same journal

Vaccines Against Pneumonia: Current Updates.

Clinics in chest medicine·2026

Same journal

Non-antibiotic Treatments for Pneumonia: Host-Directed Therapies, Next-Steps and Future Directions.

Clinics in chest medicine·2026

Same journal

Customizing Antibiotic Treatment for Pneumonia: Can We Have a Single Unified Algorithm for All Types of Pneumonia?

Clinics in chest medicine·2026

Same journal

The Role of Complex Digital Interventions to Improve Pneumonia Care.

Clinics in chest medicine·2026

See all related articles

Parkinsonian syndromes, including Parkinson's disease, can cause severe respiratory issues like impaired breathing and airway obstruction. Treatments for these conditions may also lead to drug-induced respiratory dysfunction and lung fibrosis.

Area of Science:

Neurology
Pulmonology
Pharmacology

Background:

Parkinsonian syndromes encompass idiopathic Parkinson's disease and secondary forms, characterized by motor deficits like rigidity and bradykinesia.
These syndromes are linked to increased respiratory morbidity and mortality, presenting as neuromuscular-like pulmonary function impairment.
Specific syndromes, like Multiple System Atrophy (MSA), can cause life-threatening upper airway obstruction and ventilatory control abnormalities.

Purpose of the Study:

To review the respiratory complications associated with various parkinsonian syndromes.
To examine the impact of medications used in treating parkinsonian syndromes on respiratory health.
To highlight potential life-threatening respiratory issues in patients with these neurological disorders.

Main Methods:

Related Experiment Videos

Literature review of parkinsonian syndromes and their respiratory manifestations.
Analysis of respiratory complications, including pulmonary function impairment and ventilatory control abnormalities.
Examination of drug-induced respiratory dysfunction and pulmonary toxicity from Parkinson's disease medications.

Main Results:

All parkinsonian syndromes are associated with increased respiratory mortality and can cause neuromuscular-type pulmonary dysfunction.
Upper airway obstruction and abnormal ventilatory control are significant risks, particularly in MSA.
Medications like L-dopa and dopamine agonists can induce respiratory problems, including choreiform movements, akinesia, and pleural/pulmonary fibrosis.

Conclusions:

Parkinsonian syndromes pose significant risks for respiratory complications, impacting morbidity and mortality.
Understanding these respiratory risks is crucial for managing patients with parkinsonian syndromes.
Medication side effects, including L-dopa and dopamine agonists, necessitate careful monitoring for respiratory adverse events.