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Actinobacillus (Pasteurella) ureae meningitis in a HIV-positive patient

S Kaka1, R Lunz, K P Klugman

  • 1Department of Medical Microbiology, University of the Witwatersrand, South African Institute for Medical Research, Johannesburg.

Diagnostic Microbiology and Infectious Disease
|October 1, 1994
PubMed

Insights

Actinobacillus (Pasteurella) ureae, a rare cause of meningitis, was observed in an HIV-infected patient. Head trauma or neurosurgery may contribute to this rare bacterial meningitis, which responded to antibiotics.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Neurology

Background:

  • Actinobacillus (Pasteurella) ureae is a nasopharyngeal commensal.
  • Bacterial meningitis is a serious central nervous system infection.
  • HIV infection can predispose individuals to opportunistic infections.

Observation:

  • A case of meningitis caused by Actinobacillus (Pasteurella) ureae in an HIV-infected patient is presented.
  • This rare pathogen is typically a commensal organism.
  • The patient had a history potentially involving head trauma or neurosurgery.

Findings:

  • Actinobacillus (Pasteurella) ureae can cause meningitis, particularly in immunocompromised individuals.
  • Head trauma and neurosurgical procedures are implicated as risk factors.
  • The patient received effective treatment with ceftriaxone and penicillin.

Implications:

  • Highlights the potential pathogenicity of commensal bacteria in immunocompromised hosts.
  • Suggests a need for considering Actinobacillus (Pasteurella) ureae in meningitis cases with specific risk factors.
  • Demonstrates successful treatment outcomes with standard antibiotic regimens.

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