Haemoglobin as a marker for bone marrow transplants in laboratory rats

We made use of the genetic polymorphism of haemoglobin in the laboratory rat and developed a congenic strain LEW.Hb A differing from the original LEW strain in the type of haemoglobin. The exclusion of the histoincompatibility reactions allows a long-term follow-up of the bone marrow transplants on the basis of changes in the haemoglobin pattern.