Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Critically ill Guillain Barre' syndrome

A B Taly1, S K Gupta, A Vasanth

  • 1Department of Neurology, National Institute of Mental Health & Neuro Sciences (NIMHANS), Bangalore.

The Journal of the Association of Physicians of India
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insights from Magnetic Evoked Field Analysis in Patients with Wilson's Disease.

Neurology India·2022
Same author

Recanalisation and Outcome in Cerebral Venous-sinus Thrombosis.

Annals of Indian Academy of Neurology·2022
Same author

Vitamin D and Cerebrovascular Disease.

Annals of Indian Academy of Neurology·2021
Same author

Has physical examination superannuated? …Not yet!

Neurology India·2020
Same author

Post-stroke Gait Analysis in Rehabilitation Set-up: Observational or Instrumental!

Neurology India·2019
Same author

Motor recovery and therapeutic interventions.

Neurology India·2018

Guillain-Barré Syndrome (GBS) critically ill patients often experience severe paralysis and autonomic dysfunction. Early disease course is unpredictable, requiring close monitoring and supportive care.

Area of Science:

  • Neurology
  • Critical Care Medicine

Background:

  • Guillain-Barré Syndrome (GBS) is a rare neurological disorder.
  • Critically ill GBS patients present unique management challenges.

Purpose of the Study:

  • To analyze the clinical features, management, and outcomes of critically ill GBS patients.
  • To identify predictors for ventilatory assistance and mortality in GBS.

Main Methods:

  • Retrospective analysis of 153 GBS patients over 5.5 years.
  • Detailed review of clinical data, including demographics, symptoms, CSF analysis, electromyography, and treatment outcomes for 47 critically ill patients.

Main Results:

  • 47 critically ill GBS patients (4-60 years) had frequent bulbar paralysis (42), dysautonomia (31), and need for ventilation (45).

Related Experiment Videos

  • CSF protein was elevated in 63%; electromyography showed nerve conduction abnormalities in all tested.
  • Mortality did not differ between steroid and conservative groups; no discriminant factors predicted survival or ventilation need.

    • Conclusions:

    • The course of GBS in critically ill patients is unpredictable.
    • Close supervision and meticulous supportive care are essential for managing GBS.
    • GBS remains a significant therapeutic challenge in critical care settings.