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Calcification of eccrine poroma
T Yamamoto1, A Irifune, I Katayama
1Department of Dermatology, Tokyo Medical and Dental University School of Medicine, Japan.
The Journal of Dermatology
|December 1, 1994
Summary
Two cases of eccrine poroma with calcification, a rare finding, were observed. Calcification within these sweat gland tumors is likely dystrophic, consistent with their origin.
Area of Science:
- Dermatopathology
- Oncology
Background:
- Eccrine poroma is a benign adnexal neoplasm originating from the intraepidermal eccrine sweat duct.
- Calcification within skin tumors is an uncommon phenomenon.
Observation:
- This report details two cases of eccrine poroma exhibiting calcification.
- Both cases were of the Winkelmann-MacLeod type, occurring on the face and lower leg.
- Calcification was noted within the tumor nests.
Findings:
- The observed calcification is hypothesized to be dystrophic in nature, potentially secondary to minor trauma or pressure.
- The presence of calcification in eccrine poroma, while rare, is physiologically consistent with the tumor's origin from eccrine sweat glands.
- This feature has been infrequently documented in existing literature.
Implications:
- Recognizing calcification in eccrine poroma aids in accurate histopathological diagnosis.
- Understanding the mechanism of calcification may offer insights into tumor biology.
- Further studies are warranted to explore the frequency and etiology of calcification in adnexal neoplasms.