Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The effects of cocaine on behavior maintained by timeout from avoidance

M Galizio1, M O Liborio

  • 1Department of Psychology, University of North Carolina at Wilmington 28403.

Journal of the Experimental Analysis of Behavior
|January 1, 1995
PubMed
Summary

Cocaine increased behaviors maintained by timeout from shock avoidance in rats. Stimulant drugs like cocaine affect shock avoidance differently than timeout from avoidance behaviors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laboratory lore and research practices in the experimental analysis of human behavior: Selecting reinforcers and arranging contingencies.

The Behavior analyst·2012
Same author

Analyzing the reinforcement process at the human level: can application and behavioristic interpretation replace laboratory research?

The Behavior analyst·2012
Same author

The experimental analysis of human behavior: indispensable, ancillary, or irrelevant?

The Behavior analyst·2012
Same author

Effects of MDMA, methamphetamine and methylphenidate on repeated acquisition and performance in rats.

Pharmacology, biochemistry, and behavior·2009
Same author

Chlordiazepoxide and dizocilpine, but not morphine, selectively impair acquisition under a novel repeated-acquisition and performance task in rats.

Psychopharmacology·2006
Same author

Effects of positive GABA(A) modulators on a multiple-component, repeated-acquisition test of spatial learning.

Behavioural pharmacology·2003

Area of Science:

  • Behavioral pharmacology
  • Neuroscience
  • Animal behavior studies

Background:

  • Rats were trained on concurrent schedules involving shock avoidance and timeout from avoidance.
  • Timeout from avoidance was set on variable-interval or variable-ratio schedules.

Purpose of the Study:

  • To investigate the effects of cocaine on behavior maintained by timeout from avoidance.
  • To compare cocaine's effects on timeout from avoidance versus avoidance behavior.

Main Methods:

  • Rats were exposed to concurrent schedules of avoidance and timeout from avoidance.
  • Cocaine was administered at doses ranging from 3 to 40 mg/kg.
  • Response rates for both avoidance and timeout behaviors were recorded.

Main Results:

Related Experiment Videos

  • Cocaine produced dose-dependent increases in behavior maintained by timeout from avoidance.
  • Avoidance responding also increased with cocaine, but to a lesser extent.
  • Response rate increases occurred across various doses for both interval and ratio schedules.

Conclusions:

  • Cocaine significantly enhances behavior maintained by timeout from avoidance in rats.
  • Stimulant drugs appear to affect shock avoidance and timeout from avoidance behaviors distinctly.
  • Findings suggest differential effects of stimulants on shock-postponement versus timeout from avoidance schedules.