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Risk factors for primary invasive pneumococcal disease among children in Finland

A K Takala1, J Jero, E Kela

  • 1National Public Health Institute, Department of Infectious Disease Epidemiology, Helsinki, Finland.

JAMA
|March 15, 1995
PubMed

Insights

Day care attendance significantly increases invasive pneumococcal disease risk in children under two. Frequent otitis media also poses a risk, while having younger siblings increases risk for older children.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Invasive pneumococcal disease (IPD) remains a significant public health concern in children.
  • Identifying modifiable risk factors is crucial for effective prevention strategies.

Purpose of the Study:

  • To investigate risk factors associated with invasive pneumococcal disease (IPD) in children.
  • To compare the risk posed by different childcare settings and other potential factors.

Main Methods:

  • A population-based case-control study was conducted in Finland from 1986 to 1989.
  • 149 IPD cases and 284 matched controls (children aged 0-15 years) were included.
  • Risk factors were assessed through mailed questionnaires to families.

Main Results:

  • Day care center attendance showed a substantially increased risk for IPD in children under 2 years (OR=36).
  • Family day care (OR=4.4) and a history of frequent otitis media (OR=8.8) were also significant risk factors for younger children.
  • For children aged 2 years and older, having younger siblings increased IPD risk (OR=2.2).

Conclusions:

  • Day care center attendance is a primary risk factor for IPD in children under two years.
  • The risk associated with formal day care centers is notably higher than that of family day care.
  • Early identification of children at risk can inform targeted public health interventions.
Abstract

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