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[Allergic rhinitis in children (author's transl)]

N Mygind, P Prahl

    HNO
    |April 1, 1976
    PubMed
    Summary

    Beclomethasone dipropionate nasal spray offers a safe and effective treatment for allergic nasal diseases in children and adults. This study highlights its efficacy in managing hay fever, vasomotor rhinitis, and nasal polyps with minimal systemic side effects.

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    Area of Science:

    • Allergology
    • Otorhinolaryngology
    • Pharmacology

    Background:

    • Allergic nasal diseases pose significant challenges in treatment.
    • Systemic side effects are a concern with some allergy treatments.
    • Local intranasal glucocorticosteroids offer a targeted therapeutic approach.

    Purpose of the Study:

    • To evaluate the efficacy and safety of beclomethasone dipropionate (Beconase) for allergic nasal diseases.
    • To assess the treatment of hay fever, vasomotor rhinitis, and nasal polyps.
    • To specifically investigate the use of beclomethasone dipropionate in pediatric hay fever patients.

    Main Methods:

    • A double-blind, placebo-controlled crossover trial was conducted.
    • The study involved 19 children aged 8-16 years with hay fever.
    • Participants received either beclomethasone dipropionate or a placebo intranasally.

    Main Results:

    • Beclomethasone dipropionate demonstrated high effectiveness in adult patients with hay fever, vasomotor rhinitis, and nasal polyps.
    • In the pediatric trial, 18 out of 19 children preferred the active drug over placebo.
    • No systemic side effects were reported with intranasal beclomethasone dipropionate administration.

    Conclusions:

    • Intranasal beclomethasone dipropionate is a safe and highly effective treatment for nasal hay fever symptoms in children.
    • A daily dosage of 400 µg is recommended for pediatric patients.
    • The drug provides a valuable therapeutic option for allergic rhinitis and related conditions.

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