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Effects of buspirone on influenza A virus infection in stressed mice
M Freire-Garabal1, M J Núñez, C Losada
1NIMUS, Department of Pharmacology, School of Pharmacy, Universidad de Santiago de Compostela, Spain.
Life Sciences
|January 1, 1995
Abstract:
Experiments were conducted to evaluate the effects of chronic buspirone (1 mg/kg/day) on the influenza A (PR-8/34) virus specific immune injury in CD-1 mice exposed to a chronic auditory stressor. Treatment with buspirone resulted in a decrease of the stress-induced increase of virus titers and pulmonary vascular permeability as well as in a reduction of the mortality of mice.