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Related Concept Videos

Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

1.0K
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
1.0K
Larynx01:21

Larynx

6.1K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
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Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

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Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
616
Respiratory System Abnormal Finding II: Palpation and Auscultation01:31

Respiratory System Abnormal Finding II: Palpation and Auscultation

1.9K
In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
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Physical Assessment of the Respiratory Tract IV: Auscultation01:28

Physical Assessment of the Respiratory Tract IV: Auscultation

3.3K
Auscultation is a crucial component of the physical assessment of the respiratory tract. It offers valuable insights into airflow through the bronchial tree and potential lung obstructions. This process involves careful listening to breath, voice, and adventitious sounds, which can reveal a wealth of information about a patient's respiratory health.
Breath Sounds
Breath sounds are categorized into vesicular, bronchovesicular, and bronchial.
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Related Experiment Video

Updated: Mar 25, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

677

[Laryngeal changes in mucoviscidosis]

J Tomik1, E Kotarba

  • 1Kliniki Otolaryngologicznej CM UJ, Krakowie.

Otolaryngologia Polska = the Polish Otolaryngology
|January 1, 1994
PubMed
Summary

Cystic fibrosis, a hereditary disease, rarely presents with laryngological symptoms. This study observed five children with cystic fibrosis, three with nasal polyps and two with recurrent parotid gland infections.

Area of Science:

  • Otolaryngology
  • Pediatrics
  • Genetics

Background:

  • Mucoviscidosis, also known as cystic fibrosis, is a congenital, hereditary disorder affecting exocrine glands.
  • Laryngological manifestations of cystic fibrosis are infrequently encountered in clinical practice.

Observation:

  • This study examined five pediatric patients diagnosed with cystic fibrosis.
  • Three patients underwent surgical intervention for nasal and paranasal sinus polyps.
  • Two patients were monitored for recurrent parotid gland infections.

Findings:

  • The case series highlights the occurrence of otolaryngological symptoms in pediatric cystic fibrosis patients.
  • Nasal polyposis and parotid gland infections represent potential clinical presentations.

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Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells
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The WinCF Model - An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections
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The WinCF Model - An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections

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Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
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Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells
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The WinCF Model - An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections
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Implications:

  • Increased awareness of these laryngological symptoms may aid in earlier diagnosis and management of cystic fibrosis.
  • Further research is warranted to elucidate the specific mechanisms linking cystic fibrosis to these otolaryngological issues.