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Hypoparathyroidism with extensive intracranial calcification: a case report
A Goel1, M K Bhatnagar, A Vashishta
1Department of Medicine, Lady Hardinge Medical College, New Delhi, India.
Postgraduate Medical Journal
|December 1, 1994
Summary
This study details a hypoparathyroidism case with widespread intracranial calcification. It highlights hemiballismus as a newly observed symptom, alongside epilepsy and choreoathetosis.
Area of Science:
- Neurology
- Endocrinology
- Radiology
Background:
- Hypoparathyroidism is a rare endocrine disorder characterized by insufficient parathyroid hormone production.
- Intracranial calcification is a known complication, typically affecting the basal ganglia.
- Extrapyramidal dysfunction can occur but is less commonly described.
Observation:
- A patient with hypoparathyroidism presented with extensive intracranial calcification.
- Calcification extended beyond the basal ganglia to other brain regions.
- The patient exhibited an unexplained epileptic disorder and extrapyramidal symptoms, including choreoathetosis and hemiballismus.
Findings:
- Extensive intracranial calcification in hypoparathyroidism, beyond the basal ganglia.
- Co-occurrence of epilepsy, choreoathetosis, and hemiballismus in this patient.
- Hemiballismus is reported for the first time in association with hypoparathyroidism.
Implications:
- This case expands the understanding of intracranial calcification patterns in hypoparathyroidism.
- It suggests hemiballismus may be a previously unrecognized neurological manifestation of hypoparathyroidism.
- Highlights the need for comprehensive neurological assessment in hypoparathyroidism patients.
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