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[Ketanserin and random skin flaps. An experimental study in the rat]
J Achouche1, B Teisseire, O Laccourreye
1Unité de chirurgie plastique, Hôpital Lariboisière, Université Paris VII.
Annales De Chirurgie Plastique Et Esthetique
|April 1, 1994
Abstract:
This prospective randomised study in a rodent model was designed to analyse the value of a serotonin antagonist, ketanserin, on the survival of random skin flaps in Wistar rats. Our study demonstrates the statistical value of this molecule. The surface of skin necrosis was statistically lower in the group of rats treated with pre and post operative subcutaneous injection of ketanserin.