Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Colonic lymphoma simulating cryptogenetic colitis associated with common variable hypogammaglobulinemia]

L Larvol1, J P Cervoni, M Hagiage

  • 1Service d'Hépato-Gastroentérologie, Hôpital Louis-Mourier, Colombes.

Gastroenterologie Clinique Et Biologique
|January 1, 1994
PubMed
Summary

A 72-year-old woman with late-onset common variable immunoglobulin deficiency presented with gastrointestinal symptoms. She was diagnosed with a rare colonic mucosa-associated lymphoid tissue (MALT) lymphoma, an unusual finding for this condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paecilomyces variotii Fungemia in a Patient with Lymphoma Needing Liver Transplant.

Mycopathologia·2017
Same author

[Abdominal pain, weight loss and asthenia in a 42-year-old man].

La Revue de medecine interne·2014
Same author

Immunosuppression-mediated hepatitis B reactivation diagnosed following an investigation into suspected transfusion-transmitted hepatitis B.

The Journal of hospital infection·2013
Same author

Low prevalence of colonoscopic surveillance of inflammatory bowel disease patients with longstanding extensive colitis: a clinical practice survey nested in the CESAME cohort.

Alimentary pharmacology & therapeutics·2011
Same author

[Fever and abdominal pain in a 56-year-old woman].

La Revue de medecine interne·2009
Same author

Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease: a randomised, double blind, placebo controlled GETAID trial.

Gut·2005

Area of Science:

  • Gastroenterology
  • Hematology
  • Immunology

Background:

  • Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by low immunoglobulin levels and impaired B-cell function.
  • Late-onset CVID is less common and can present with diverse clinical manifestations, including gastrointestinal issues.
  • Colonic lymphomas are rare, with MALT lymphomas being an uncommon subtype, particularly in the colon.

Observation:

  • A 72-year-old female patient with known late-onset CVID was hospitalized due to diarrhea and fever.
  • Colonoscopy revealed aphthoid and deep ulcerations throughout the colon, mimicking inflammatory bowel disease like Crohn's disease.
  • Histological and immunohistochemical analyses confirmed the presence of a low-grade B-cell MALT lymphoma.

Findings:

Related Experiment Videos

  • The patient's presentation highlights an unusual manifestation of colonic lymphoma.
  • This case represents the second documented instance of colonic lymphoma associated with late-onset CVID.
  • The findings underscore the importance of considering lymphoproliferative disorders in CVID patients with unexplained gastrointestinal pathology.

    • Implications:

    • This case expands the spectrum of gastrointestinal complications associated with CVID.
    • It emphasizes the need for thorough investigation, including biopsy, in CVID patients presenting with colonic ulcerations.
    • Further research into the association between CVID and gastrointestinal MALT lymphomas may improve diagnostic and therapeutic strategies.