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[Rhabdomyosarcoma of the prostate and bladder in a child: radical or conservative surgery?]
M I Carvajal Busslinger1, J Plaschkes
1Chirurgische Universitäts-Kinderklinik, Inselspital, Bern.
Insights
Rhabdomyosarcoma treatment in infants has advanced, with chemotherapy enabling tumor eradication while preserving function. Two pediatric cases of bladder-prostata rhabdomyosarcoma highlight successful outcomes with both surgical and non-surgical approaches.
Area of Science:
- Pediatric Oncology
- Surgical Oncology
- Pediatric Urology
Context:
- Rhabdomyosarcoma is the most common pediatric soft-tissue tumor.
- Infantile rhabdomyosarcoma frequently occurs in the pelvic region, specifically the bladder or prostate.
- Treatment aims to achieve complete tumor removal while preserving organ function.
Purpose:
- To evaluate treatment strategies for bladder-prostata rhabdomyosarcoma in infants.
- To compare outcomes of radical surgery with conservative, chemotherapy-based approaches.
- To assess long-term tumor control and functional preservation.
Summary:
- Presents two cases of pediatric bladder-prostata rhabdomyosarcoma.
- Case 1 (1983): Underwent chemotherapy and cystoprostatectomy.
- Case 2 (1991): Treated with chemotherapy and tumor eradication without cystectomy.
- Both patients achieved long-term tumor remission (10 and 2 years, respectively).
Impact:
- Demonstrates the efficacy of preoperative chemotherapy in pediatric rhabdomyosarcoma.
- Highlights the feasibility of function-sparing treatments for bladder-prostata rhabdomyosarcoma.
- Provides evidence for successful outcomes in both radical and conservative treatment paradigms.
Abstract:
Rhabdomyosarcoma is the most common soft-tissue tumor in childhood. In infants it is frequently localized in the pelvis and in the prostata or bladder region. The aim of treatment should be to eradicate the tumor and yet maintain as normal function as possible. Effective preoperative chemotherapy has enabled one to frequently achieve this aim. We report on two patients both with a rhabdomyosarcoma of the bladder-prostata. One of them in 1983 was operated and treated with chemotherapy and cysto-prostatectomy and the other in 1991 with chemotherapy and eradication of the tumor without cystectomy. Both children are now tumor-free after 10 years/2 years resp. Both approaches are discussed.