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[Hemodynamic properties of the hemopump]
T Mihaljevic1, B Leskosek, L K von Segesser
1Department Chirurgie, Universitätsspital Zürich.
Helvetica Chirurgica Acta
|December 1, 1994
Summary
This study found that afterload significantly impacts Hemopump HP 31 flow, while hematocrit does not. Reducing afterload can improve Hemopump performance and oxygen delivery.
Area of Science:
- Cardiovascular Engineering
- Biomedical Engineering
- Hemodynamics
Context:
- The Hemopump HP 31 is an advanced catheter-mounted, transvalvular left ventricular assist device.
- It is designed for insertion into the left ventricle via the ascending aorta.
Purpose:
- To investigate the effects of hematocrit and afterload on the Hemopump HP 31's pump flow.
- To develop a nomogram for predicting in vivo pump performance.
Summary:
- The Hemopump HP 31 was tested using bovine blood across various hematocrit levels (16-40%) and afterload pressures (40-120 mm Hg).
- Afterload significantly reduced pump flow (p < 0.001), with a 24% decrease at 120 mm Hg.
- Hematocrit levels did not significantly affect pump flow (p = 0.72).
Impact:
- Findings enable nomogram creation for in vivo Hemopump flow prediction.
- Reducing afterload is crucial for improving Hemopump performance, especially during patient weaning.
- Increasing hematocrit may enhance oxygen delivery without compromising pump function.