Psychological influences in disease: a decision theory model

The integrity of living organisms depends on analyzing information from an uncertain and hostile world and responding appropriately to it. Statistical decision theory indicates that an optimum decision strategy takes into account information, probability and subjective values ascribed to correct and incorrect responses. It follows that decisions at all levels, including the molecular level, can be strongly influenced by psychological and emotional states which influence subjective evaluation. This concept provides a framework within which psychological influences in disease can be analyzed.