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[Intra-and extracranial chondrosarcoma]

T Tanaka¹, S Tani, S Nakahara

¹Department of Neurosurgery, Jikei University School of Medicine, Tokyo, Japan.

No Shinkei Geka. Neurological Surgery

|February 1, 1995

Summary

A rare case of a 17-year-old female with a parasellar chondrosarcoma is presented. Magnetic resonance imaging (MRI) was crucial for diagnosis, distinguishing it from chordoma.

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Area of Science:

Neuro-oncology
Neurosurgery
Radiology

Background:

A 17-year-old female presented with diplopia and gait disturbance.
Initial computed tomography (CT) failed to detect a right parasellar mass, but magnetic resonance imaging (MRI) revealed it.

Observation:

Seven years later, the patient developed progressive gait disturbance, lower cranial nerve palsy, and cerebellar signs.
CT scans showed a large low-density area with calcification extending from the parasellar region to the midbrain.

Findings:

Surgical removal was performed via a combined translabyrinthine and epidural subtemporal approach.
Histological examination diagnosed a well-differentiated chondrosarcoma, confirmed by electron microscopy showing chondrocyte features.

Implications:

Distinguishing chondrosarcoma from chordoma is critical due to differing treatment strategies and prognoses.
MRI is a valuable initial tool for differentiating these parasellar tumors.

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