[Catastrophic antiphospholipid syndrome. Presentation of a case]

The case of a 35 years old female patient is here reported. Her previous medical records included repeated miscarriages and ischaemic ulcers in the right leg. She developed thrombosis at the left common femoral artery with serum antiphospholipid antibodies. The patient was treated with anticoagulants and two months later developed multiorganic failure. She was successfully managed with plasmapheresis, high dose prednisone, and anticoagulants. The clinical picture was considered to be a catastrophic antiphospholipid syndrome.