Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting

INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.

Oncogene·2017

ROCK2/rasHa co-operation induces malignant conversion via p53 loss, elevated NF-κB and tenascin C-associated rigidity, but p21 inhibits ROCK2/NF-κB-mediated progression.

Oncogene·2016

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.

Oncogene·2015

PTEN ablation in Ras(Ha)/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition.

Oncogene·2013

Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.

Oncogene·2011

Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.

Oncogene·2011

Cancer immunotherapy with oncolytic myxoma virus.

Advances in cancer research·2026

Cancer terminator viruses: Unique conditionally replication competent oncolytic viruses producing therapeutic anti-cancer immunomodulating agents.

Advances in cancer research·2026

Advancing clinical translation of oncolytic adenoviruses.

Advances in cancer research·2026

Operation oncolysis: Reoviruses in the theater of cancer war.

Advances in cancer research·2026

AAV vectors for cancer gene therapy.

Advances in cancer research·2026

Vesicular stomatitis virus (VSV) as an oncolytic therapeutic agent for cancer.

Advances in cancer research·2026

Assessment of Natural Killer Cell Serial Degranulation.

Current protocols·2026

Oncogenic KRAS Rewires mRNA Stability and Translation through AGO2-Mediated Disruption of the miRNA pathway.

Cancer research·2026

Stimuli-responsive nanocarriers for precision cation channel therapy.

Chemical communications (Cambridge, England)·2026

Disruption of hippocampal upstream regulators of mTOR and insulin pathways in Down syndrome with Alzheimer's disease neuropathology: Preliminary observations.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

ATF7 drives diabetic wound healing via NOTCH1 repression and N1ICD-dependent macrophage polarization control.

JCI insight·2026

Innate immune sensor NOD2 promotes cartilage degradation and osteoarthritis progression by stabilizing TRAF6 in chondrocytes.

JCI insight·2026

Related Experiment Videos

Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting

Related Concept Videos

INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.

ROCK2/rasHa co-operation induces malignant conversion via p53 loss, elevated NF-κB and tenascin C-associated rigidity, but p21 inhibits ROCK2/NF-κB-mediated progression.

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.

PTEN ablation in Ras(Ha)/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition.

Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.

Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.

Cancer immunotherapy with oncolytic myxoma virus.

Cancer terminator viruses: Unique conditionally replication competent oncolytic viruses producing therapeutic anti-cancer immunomodulating agents.

Advancing clinical translation of oncolytic adenoviruses.

Operation oncolysis: Reoviruses in the theater of cancer war.

AAV vectors for cancer gene therapy.

Vesicular stomatitis virus (VSV) as an oncolytic therapeutic agent for cancer.

Assessment of Natural Killer Cell Serial Degranulation.

Oncogenic KRAS Rewires mRNA Stability and Translation through AGO2-Mediated Disruption of the miRNA pathway.

Stimuli-responsive nanocarriers for precision cation channel therapy.

Disruption of hippocampal upstream regulators of mTOR and insulin pathways in Down syndrome with Alzheimer's disease neuropathology: Preliminary observations.

ATF7 drives diabetic wound healing via NOTCH1 repression and N1ICD-dependent macrophage polarization control.

Innate immune sensor NOD2 promotes cartilage degradation and osteoarthritis progression by stabilizing TRAF6 in chondrocytes.

Related Experiment Videos

Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting

Related Concept Videos

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