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Updated: Aug 8, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
Hip involvement in early rheumatoid arthritis
K Eberhardt1, E Fex, K Johnsson
1Department of Rheumatology, Lund University Hospital, Sweden.
Early hip joint destruction is common in rheumatoid arthritis (RA). Ultrasonography can detect hip synovitis in RA patients, even when symptoms are mild or absent, enabling earlier treatment.
Area of Science:
- Rheumatology
- Orthopedics
- Medical Imaging
Background:
- Rheumatoid arthritis (RA) frequently leads to hip joint destruction.
- Clinical symptoms of hip involvement in RA often manifest late in the disease progression.
Purpose of the Study:
- To investigate early hip involvement in rheumatoid arthritis (RA).
- To assess the efficacy of ultrasonography in detecting hip joint synovitis in RA patients.
Main Methods:
- Study I: Monitored hip replacements in 113 RA patients with disease duration over five years.
- Study II: Evaluated ultrasonography for hip synovitis in 76 RA patients, comparing findings with clinical data and radiographs.
Main Results:
- Twenty-one hip replacements were performed in 15 patients, with a median disease duration of 48 months at the time of the first surgery.
- High disease activity predicted the need for hip arthroplasty.
- Ultrasonography identified hip synovitis in 13 patients, with nine showing bilateral involvement; seven of these were asymptomatic.
- Clinical assessment alone was insufficient to diagnose hip synovitis, as some patients with positive ultrasound findings were asymptomatic or had mild symptoms.
Conclusions:
- Early hip joint destruction is prevalent in RA, with symptoms often appearing late.
- Ultrasonography is a valuable tool for identifying hip joint involvement in RA, surpassing clinical signs and symptoms.
- Ultrasonographic detection of synovitis can guide early therapeutic interventions in RA patients.
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