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Regulation of translation and cell growth by eIF-4E
1Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
Biochimie
|January 1, 1994
Abstract:
This review discusses the regulation of a key controlling step in the initiation of protein synthesis, the binding of mRNA to ribosomes. Particular focus is given to the phosphorylation of the cap-binding factor, eIF-4E, and the role of this factor in the regulation of cell growth.