Clinical breast cancer research core

Area of Science:

• Oncology
• Clinical Research
• Biorepositories

Background:

• Breast cancer research requires robust infrastructure for clinical studies.
• Translational research necessitates integrated clinical data and biospecimens.
• The development of prognostic and therapeutic markers requires clinical validation.

Purpose of the Study:

• To establish a dedicated clinical research facility for breast cancer studies.
• To create a comprehensive clinical database linked to a tumor bank.
• To develop and maintain a serum and DNA lymphocyte bank for biomarker evaluation.

Main Methods:

• Providing investigators access to a clinical research facility.
• Linking a clinical database with a tumor bank for data integration.
• Establishing and maintaining a biorepository for serum and DNA samples.

Main Results:

• Facilitated access to clinical research infrastructure for SPORE investigators.
• Enabled integrated studies using a linked clinical database and tumor bank.
• Created a valuable resource for evaluating laboratory-developed prognostic and therapy response factors.

Conclusions:

• The clinical breast cancer research core effectively supports translational research.
• The integrated resources enhance the ability to improve breast cancer diagnosis and prognosis.
• The biorepository provides a critical link for validating biomarkers in a clinical setting.