Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deliberate mild hypothermia

D I Sessler1

  • 1Department of Anesthesia, University of California, San Francisco 94143-0648.

Journal of Neurosurgical Anesthesiology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

General anesthetics impair the body's temperature regulation. Mild hypothermia, used in neurosurgery for brain protection, requires careful management due to potential complications and the need for rewarming.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postoperative pulmonary complications in older patients undergoing elective surgery with a supraglottic airway device or tracheal intubation.

Anaesthesia·2023
Same author

Machine learning to predict myocardial injury and death after non-cardiac surgery.

Anaesthesia·2023
Same author

A randomised controlled trial of dexmedetomidine for delirium in adults undergoing heart valve surgery.

Anaesthesia·2023
Same author

Humidity and measurement of volatile propofol using MCC-IMS (EDMON).

Journal of clinical monitoring and computing·2022
Same author

Hydroxyethyl starch on kidney and haemostatic function in cardiac surgical patients: is a non-inferiority study design appropriate for this setting? A reply.

Anaesthesia·2021
Same author

The role of routine postoperative troponin measurement in the diagnosis and management of myocardial injury after non-cardiac surgery.

Anaesthesia·2020
Same journal

Viscoelastic Hemostatic Assays in Spine Surgery: A Scoping Review of Perioperative Transfusion Practices and Coagulation Assessment.

Journal of neurosurgical anesthesiology·2026
Same journal

Hormonal Status as an Uncontrolled Variable in the Assessment of Aprepitant Efficacy for PONV Following Acoustic Neuroma Surgery.

Journal of neurosurgical anesthesiology·2026
Same journal

Challenges in Processed EEG Interpretation: The Influence of Intraoperative Neuromonitoring (IONM) and Chronic Opioid Use.

Journal of neurosurgical anesthesiology·2026
Same journal

Methodological Definition and Validation of the Intracranial Pressure-End-Tidal CO2 Slope (IESlope): Characterization and Clinical Relevance in Traumatic Brain Injury.

Journal of neurosurgical anesthesiology·2026
Same journal

Exploring the Landscape of Neuroanesthesia Quality Improvement Structure, Processes, and Outcomes: A Pilot Survey.

Journal of neurosurgical anesthesiology·2026
Same journal

Knowledge Decay Following External Ventricular Drain Education: A Survey of Perioperative Clinicians.

Journal of neurosurgical anesthesiology·2026
See all related articles

Area of Science:

  • Anesthesiology
  • Physiology
  • Neurosurgery

Background:

  • Core body temperature is tightly regulated by thermoregulatory responses.
  • General anesthetics significantly impair thermoregulatory control, widening the temperature range that doesn't trigger protective responses.
  • Thermoregulatory control is a key factor in intraoperative temperature fluctuations.

Purpose of the Study:

  • To examine the impact of general anesthetics on thermoregulation.
  • To discuss the application and management of mild hypothermia in neurosurgery.
  • To highlight the benefits and complications associated with therapeutic hypothermia.

Main Methods:

  • Review of the effects of general anesthetics on thermoregulatory responses.
  • Analysis of passive and active cooling methods for inducing hypothermia.

Related Experiment Videos

  • Discussion of clinical implications and complications of mild hypothermia.

    • Main Results:

    • General anesthetics increase the threshold for triggering thermoregulatory responses by approximately 20-fold.
    • Mild hypothermia (around 34°C) can be achieved passively with anesthesia or neurosurgery.
    • Active cooling, such as forced air, is effective for rapid or deeper hypothermia (near 32°C).

    Conclusions:

    • Mild hypothermia offers significant neuroprotection against cerebral ischemia, making it valuable in neurosurgery.
    • Therapeutic hypothermia is associated with risks including myocardial ischemia, infection, coagulopathy, and shivering.
    • Patients undergoing deliberate hypothermia require subsequent active rewarming to mitigate complications.