[Use of insoles made of antimicrobial materials as prophylactic means in foot mycoses]
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Abstract:
Stationary dermatologic examination covered 32 sufferers from epidermophytosis of soles, who used 3 types of antimicrobial insoles chosen through laboratory investigations. Clinical trials proved that antimicrobial insoles, if applied during 2 weeks, result in considerably decreased occurrence of causal fungus in the patients' surface skin scarring. The results proved fungicidal and bactericidal activity of insoles including furagin, nitrofurilacroleine, polyhexamethylene guanidine, so such insoles could be recommended as prophylactic measure for mycoses of soles.
Insights
Antimicrobial insoles containing furagin, nitrofurilacroleine, and polyhexamethylene guanidine significantly reduced fungal infections on soles within two weeks. These insoles show promise for preventing fungal infections of the feet.
Area of Science:
- Dermatology
- Mycology
- Antimicrobial agents
Background:
- Epidermophytosis of the soles is a common fungal infection.
- Antimicrobial treatments are crucial for managing and preventing foot mycoses.
Purpose of the Study:
- To evaluate the efficacy of three types of antimicrobial insoles in treating epidermophytosis of the soles.
- To determine the fungicidal and bactericidal properties of specific antimicrobial agents in insoles.
Main Methods:
- A clinical trial involving 32 patients with epidermophytosis of the soles.
- Laboratory investigations to select three types of antimicrobial insoles.
- Two-week application period of antimicrobial insoles.
Main Results:
- A considerable decrease in the occurrence of causal fungus on patients' skin was observed.
- The insoles demonstrated significant fungicidal and bactericidal activity.
- Insoles containing furagin, nitrofurilacroleine, and polyhexamethylene guanidine were effective.
Conclusions:
- Antimicrobial insoles are effective in reducing fungal load on the soles.
- These insoles can be recommended as a prophylactic measure against foot mycoses.
- The tested antimicrobial agents exhibit potent activity against causative agents of epidermophytosis.