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The carboxyphosphonoenolpyruvate synthase-encoding gene from the bialaphos-producing organism Streptomyces
S H Lee1, T Hidaka, H Nakashita
1Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan.
Gene
|February 3, 1995
Abstract:
The nucleotide (nt) sequence of the Streptomyces hygroscopicus gene encoding carboxyphosphonoenolpyruvate (CPEP) synthase, that catalyzes a transesterification between phosphoenolpyruvate (PEP) and phosphonoformate (PF) in the bialaphos biosynthetic pathway, has been determined. The amino-acid sequence deduced from the nt sequence is similar to several eukaryotic 2-phospho-D-glycerate hydrolases (EC 4.2.1.11).