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Related Experiment Videos

[Aortic root replacement in twin Marfan patients]

A Sasaki1, H Doi, K Sugiki

  • 1Department of Cardiovascular Surgery, Hokkaido Ohno Hospital, Sapporo, Japan.

[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
|January 1, 1995
PubMed
Summary

Aortic root replacement using composite valve grafts was successfully performed in 33-year-old Marfan syndrome twins. Long-term cardiovascular surveillance is recommended for these patients.

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Area of Science:

  • Cardiovascular Surgery
  • Genetics
  • Marfan Syndrome

Background:

  • Marfan syndrome is a genetic disorder affecting connective tissue, often leading to aortic root dilation and dissection.
  • Aortic root ectasia and insufficiency pose significant risks, necessitating surgical intervention.

Observation:

  • Two 33-year-old male twins with Marfan syndrome presented with annuloaortic ectasia (aortic diameters 6.4 and 6.8 cm) and moderate aortic insufficiency.
  • One twin experienced preoperative pneumonia, while the other was asymptomatic.

Findings:

  • Aortic root replacement was performed using composite valve grafts with Carrel's patch technique for coronary reimplantation.
  • Both patients had a satisfactory postoperative recovery.

Implications:

  • Composite valve grafting is an effective surgical option for Marfan syndrome patients with aortic root pathology.
  • Lifelong surveillance with MRI and CT is crucial to monitor for potential late aortic dissections or aneurysms in other aortic segments.

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