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Published on: February 9, 2016
Development of gastroscopic food sensitivity testing in dogs
W G Guilford1, D R Strombeck, Q Rogers
1Department of VM Physiology and VM Medicine, University of California, Davis.
Journal of Veterinary Internal Medicine
|November 1, 1994
Summary
Gastroscopic food sensitivity testing (GFST) in dogs shows promise for diagnosing gastrointestinal food sensitivities. Pre-testing with a hypoallergenic diet may enhance GFST accuracy for detecting immediate food sensitivities.
Area of Science:
- Veterinary Medicine
- Gastroenterology
- Immunology
Background:
- Food sensitivities are a common concern in canine health.
- Accurate diagnostic methods for gastrointestinal food sensitivities are needed.
- Current diagnostic approaches may have limitations.
Purpose of the Study:
- To develop a clinical gastroscopic food sensitivity testing (GFST) technique for dogs.
- To evaluate the effect of a hypoallergenic diet (
- unmasking
- ) on GFST results.
Main Methods:
- GFST technique developed using endoscopies in healthy dogs.
- Food extracts applied directly to the stomach lining via endoscope.
- Observed mucosal and peristaltic changes within minutes.
- Tested the effect of a hypoallergenic diet prior to GFST in atopic and healthy dogs.
Main Results:
- Localized swelling and erythema were key indicators of positive reactions.
- No reactions observed with a negative control (lamb extract).
- Hypoallergenic diet "unmasking" increased the number of positive GFST results.
- GFST results correlated with positive oral food challenges.
Conclusions:
- GFST is a promising tool for diagnosing immediate gastrointestinal food sensitivities in dogs.
- Preceding GFST with a hypoallergenic diet appears to enhance diagnostic sensitivity.
- Further research is warranted to validate GFST in a larger canine population.
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