[Sleep endocrinology]
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Updated: Aug 14, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
Published on: September 22, 2020
1Max-Planck-Institut für Psychiatrie, Klinisches Institut, München.
Abstract:
Human sleep is characterized by the cyclic occurrence of episodes of non-REM and REM sleep and by distinct secretory patterns of several hormones. During depression and aging there are similar changes in the neurophysiological and the neuroendocrine components of sleep. A review of data deriving from clinical studies in patients and controls and from animal research supports the view of a bidirectional interaction between sleep structure and nocturnal hormone secretion. These data suggest that changes in the activity of neurohormones have a key role in the development of aberrant sleep during depression and during aging.
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