Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic hepatitis caused by lisinopril

H T Droste1, R A de Vries

  • 1Department of Internal Medicine, Rijnstate Hospital, Arnhem, Netherlands.

The Netherlands Journal of Medicine
|February 1, 1995
PubMed
Summary

Angiotensin-converting enzyme (ACE) inhibitors can rarely cause severe liver damage. This case report details a patient who developed chronic liver injury from lisinopril, a commonly prescribed ACE inhibitor.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurological symptoms and cerebrovascular accidents: manifestations of left-sided cardiac tumours in adults.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2015
Same author

Possible complications of subclavian crush syndrome.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2015
Same author

The biological effects of radiation.

The International journal of risk & safety in medicine·2013
Same author

Predictors for neoplastic progression in patients with Barrett's Esophagus: a prospective cohort study.

The American journal of gastroenterology·2011
Same author

Renal infarction after cocaine abuse: a case report and review.

Clinical nephrology·2009
Same author

Vitamin K deficiency bleeding in cholestatic infants with alpha-1-antitrypsin deficiency.

Archives of disease in childhood. Fetal and neonatal edition·2009

Area of Science:

  • Pharmacology
  • Hepatology
  • Cardiology

Background:

  • Angiotensin-converting enzyme (ACE) inhibitors are widely prescribed for hypertension and cardiac failure.
  • While generally safe, ACE inhibitors are associated with rare but serious adverse effects.
  • Hepatotoxicity is a recognized, albeit infrequent, complication of this drug class.

Observation:

  • This report details a specific case of a patient experiencing adverse effects from ACE inhibitor therapy.
  • The patient presented with chronic liver damage.
  • The observed liver injury was attributed to the use of lisinopril.

Findings:

  • Lisinopril, an ACE inhibitor, was identified as the causative agent for chronic liver damage in this patient.
  • The case highlights a rare but significant side effect of lisinopril therapy.
  • The liver injury developed over the course of treatment with the drug.

Implications:

  • This case underscores the importance of monitoring liver function in patients receiving ACE inhibitors, particularly lisinopril.
  • Physicians should consider drug-induced liver injury in patients presenting with unexplained chronic liver damage while on ACE inhibitors.
  • Further investigation into the mechanisms of ACE inhibitor-induced hepatotoxicity may be warranted.

Related Experiment Videos